Bisoprolol hemifumarate USP

Bisoprolol hemifumarate USP) Tablet5mg/2.5mg DESCRIPTION Bisoprolol is the most potent β1-selective β-blocker. It has the highest level of β1-selectivity and by blocking the heart’s β1 adrenergic receptors it reduces heart rate & force of contraction of the heart, thus lowers blood pressure. COMPOSITION Bisoprolol 2.5: Each film-coated tablet contains Bisoprolol hemifumarate USP 2.5 mg. Betabis 5: Each film-coated tablet contains Bisoprolol hemifumarate USP 5 mg. INDICATIONS (Bisoprolol) is indicated in the management of hypertension, angina. It may be used alone or in combination with other antihypertensive agents. DOSAGE AND ADMINISTRATION The dose of Betabis must be individualized to the needs of the patient. The usual starting dose is Betabis 5 mg once daily. In some patients, Betabis 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of Betabis 5 mg is inadequate, the dose may be increased to Betabis 10 mg and then, if necessary, to 20 mg once daily. Patients with renal or Hepatic Impairment : In patients with hepatic impairment (hepatitis or cirrhossis) or renal dysfunction (creatinine clearance